Effect of anesthesia mode during endovascular treatment on neurological functional outcomes in patients with acute posterior circulation stroke
10.3724/zdxbyxb-2023-0453
- VernacularTitle:麻醉方式对急性后循环脑卒中血管内治疗患者神经功能结局的影响
- Author:
Xiaofeng ZHU
1
,
2
;
Zheyu ZHANG
;
Wansi ZHONG
;
Yaode HE
;
Zhongyu LUO
;
Ningyuan ZHANG
;
Chaochan CHENG
;
Jianhong YANG
;
Min LOU
Author Information
1. 浙江大学医学院附属第二医院神经内科,浙江 杭州 310009
2. 桐乡市第一人民医院神经内科,浙江 嘉兴 314500
- Keywords:
Stroke;
Endovascular treatment;
General anesthesia;
Conscious sedation;
Retrospective study
- From:
Journal of Zhejiang University. Medical sciences
2024;53(2):151-159
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the effect of anesthesia mode on the neurological functional outcomes in patients undergoing endovascular treatment for acute posterior circulation ischemic stroke.Methods:Clinical data of 656 patients undergoing intravascular therapy for acute posterior circulation ischemic stroke registered in online Acute Stroke Patients for Stroke Management Quality Evaluation Database from January 2017 to December 2022 were retrospectively analyzed.The data included 163 cases with conscious sedation and 493 cases with general anesthesia during the procedure.After propensity score matching,428 patients were included in the analysis,including 155 cases in the conscious sedation group and 273 cases in the general anesthesia group.The differences of operation mode,etiology type,vascular recanalization,hemorrhagic transformation at 24 h,modified Rankin Scale(mRS)score at 3 months and mortality within 3 months were compared between the two groups.Binary logistic regression was used to explore the effect of different anesthesia mode on neurological functional outcomes.Results:There was a significant difference in operation mode between the two groups(P<0.01),while there were no significant differences in etiology type,vascular recanalization,hemorrhagic transformation at 24 h,mRS score at 3 months or mortality within 3 months(all P>0.05).Binary logistic regression analysis revealed that anesthesia modes were not significantly associated with functional outcomes of patients(OR=1.151,95%CI:0.751-1.765,P>0.05).Conclusion:Anesthesia mode(conscious sedation or general anesthesia)will not affect the neurological functional outcomes in patients with acute posterior circulation ischemic stroke undergoing endovascular treatment.
