The epidemiological characteristics and adherence to hypoglycemic agents of ischemic stroke patients with diabetes
10.3760/cma.j.cn112150-20210530-00523
- VernacularTitle:中国合并糖尿病的缺血型脑卒中患者分布特征及其对降血糖药物的依从性研究
- Author:
Jian GUO
1
;
Tianjia GUAN
;
Longde WANG
;
Baohua CHAO
;
Yuanli LIU
Author Information
1. 中国医学科学院北京协和医学院 北京协和医院心内科 医学科学研究中心，北京100730
- Keywords:
Stroke;
Diabetes mellitus;
Cross-sectional studies;
Secondary prevention
- From:
Chinese Journal of Preventive Medicine
2021;55(8):952-957
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the epidemiological characteristics and adherence to hypoglycemic agents of the ischemic stroke patients combined with diabetes.Methods:The study recruited 23 044 ischemic stroke cases from 2013-2015 screening period of China National Stroke Screening Survey. Standardized questionnaires were used to obtain information on demographic data, stroke history, the presence of influence factors, as well as the type of stroke, diagnosis date, frequency, chronic diseases history and hypoglycemic therapy. We used logistics model to investigate the possible risk factors of ischemic stroke combined with diabetes, and calculated the population attributable risk proportion ( PARP). We also investigate the adherence to hypoglycemic agents. Results:The mean age of 23 044 ischemic stroke patients was (64.99±9.42) years old, 50.91% were males (11 731). In ischemic stroke patients, 21.52% had diabetes. According to the results of logistics model, ischemic stroke patients with hypertension, dyslipidemia, atrial fibrillation or family history of stroke had higher risk to combine with diabetes, their Odds Ratios ( OR) were 2.18 (1.87-2.55), 1.99 (1.78-2.23), 1.64 (1.39-1.92) and 1.19 (1.06-1.33). Considering the prevalence of each influence factor in ischemic stroke patients, atrial fibrillation had the highest PARP (95% CI) of 62.65% (61.27%-63.76%). In ischemic stroke patients combined with diabetes, 70.73% (3 463/4 896) had taken hypoglycemic agents. Conclusion:There still were a large number of ischemic stroke patients combined with diabetes and a low rate of adherence to hypoglycemic agents.
