Effect of spinal manipulation on brain functional activity in patients with lumbar disc herniation
10.3785/j.issn.1008-9292.2015.03.002
- VernacularTitle:脊柱推拿对腰椎间盘突出症患者脑功能活动的影响
- Author:
Wei-An YUAN
1
;
Zhi-Bi SHEN
;
Li XUE
;
Wen-Li TAN
;
Ying-Wu CHENG
;
Song-Hua ZHAN
;
Hong-Sheng ZHAN
Author Information
1. 上海中医药大学附属曙光医院石氏伤科医学中心
- Keywords:
Manipulation,spinal;
Lumbar vertebrae;
Intervertebral disk displacement /AN MO LIAO FA;
Magnetic resonance imaging;
Brain;
Pain;
Treatment outcome
- From:
Journal of Zhejiang University. Medical sciences
2015;(2):124-130,137
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of spinal manipulation ( SM) on brain functional activity in patients with lumbar disc herniation ( LDH ) .Methods:Eleven patients with LDH were recruited in the study .All patients received 6 times of lumbar SM treatment and then clinical efficacy was evaluated .All patients received brain functional magnetic resonance imaging ( fMRI ) scans before and after SM treatment.Results: Three subjects dropped out and 8 subjects completed the study , among whom 4 cases were effective and 4 ineffective after SM treatment .The required pressure value producing the same level ( VAS 50 ) pain was ( 7 .43 ±1 .47 ) kg and (10.53 ±0.55) kg before and after SM treatment in effective patients ( P<0.05);however , there was no significant difference in ineffective patients ( P>0 .05 ) . Compared to pre-treatment level, the brain functional activity in effective patients was mainly inhibited , the inhibited areas were located in the right side of prefrontal cortex and cerebellum;while the brain functional activity was generally enhanced in ineffective patients.Conclusion:SM can affect the brain functional activity of patients with LDH , the inhibited areas is mainly located in prefrontal cortex and cerebellum when SM treatment is effective .
