Association between elevated blood pressure and high carotid intima-media thickness in children according to different blood pressure references
10.3760/cma.j.cn112150-20200610-00859
- VernacularTitle:基于不同标准判定的儿童血压偏高与颈动脉内中膜增厚的关联
- Author:
Liangkai ZHANG
1
;
Yanqing ZHANG
;
Qian ZHANG
;
Jiahong SUN
;
Min ZHAO
;
Bo XI
Author Information
1. 山东大学齐鲁医学院公共卫生学院流行病学系 山东大学儿童心血管研究中心，济南 250012
- Keywords:
Child;
Blood pressure;
Cross-sectional studies;
Carotid intima-media thickness
- From:
Chinese Journal of Preventive Medicine
2020;54(12):1396-1401
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the association between elevated blood pressure (BP) and carotid intima-media thickness (cIMT) in children according to four BP references.Methods:Study population came from"Huantai Childhood Cardiovascular Health Cohort Study"in Huantai County, Zibo City, Shandong Province. A convenient cluster sampling method was used to conduct a cross-sectional survey on 1 515 children from November 2017 to January 2018 in a primary school. A total of 1 431 children aged 6-11 years old with complete data were included in this study. Data on demographic characteristics, BP and cIMT were collected through questionnaire survey, physical examination and ultrasound examination. High cIMT was defined as the level of cIMT ≥ age-and sex-specific 90 th percentile of this study population. Based on the Chinese Guideline reference, the Health Industry reference, the International reference and the U.S. reference, all participants were divided into three subgroups: the normal BP, high normal BP and, elevated BP. The multivariate logistic regression models were used to examine the association between BP status and high cIMT in children. Results:The age of children was (8.9±1.5) years, and boys accounted for 53.4% ( n=682). The multivariate logistic regression models showed that after adjusting for relevant confounding factors, the risk of high cIMT in elevated BP group was increased compared with the normal BP group according to the four references (all P values<0.05) Conclusion:Elevated BP according to the four BP references is associated with high cIMT in children.
