Histopathological Findings of Schnyder's Crystalline Corneal Dystrophy.
- Author:
Jun Hyung KIM
1
;
Yoon Won MYONG
Author Information
1. Department of Ophthalmology, St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Corneal opacity;
Lipid deposits;
Schnyder's crystalline dystrophy
- MeSH:
Adolescent;
Adult;
Cholesterol;
Corneal Opacity;
Corneal Transplantation;
Crystallins*;
Epithelium;
Genetic Diseases, Inborn;
Humans;
Korea;
Microscopy, Electron;
Vacuoles
- From:Journal of the Korean Ophthalmological Society
1995;36(8):1363-1369
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Schnyder's crystalline corneal dystrophy is a hereditary disease of unknown etiology, and characterized by bilateral subepithelial corneal opacification with crystalline or diffuse deposits of cholesterol or other lipid. It is rare and has never been reported in Korea. The authors experienced a case of Schnyder's crystallin corneal dystrophy examined in a 36-year-old man who had bilateral corneal crystalline deposits since 15 years old and significant reduction in vision for two years. Light microscopic examination of patient's keratoplasty specimen showed lipid deposits in the superficial stroma, and electron microscopy disclosed multiple lipid vacuoles in basal epithelium, Bowman slayer, superficial stroma and keratocytes. In this report, we describe the histopathological findings of Schnyder's crystalline corneal dystrophy.
