A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS

ZHANG YI; QUAN ZHIYAN; LOU FEIYANG; FANG YUJIAO; JTHOMPSON GARTH; CHEN GAO; ZHANG XIAOTONG

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A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS

Author: ZHANG YI ^{1
,

2
,

3} ; QUAN ZHIYAN ; LOU FEIYANG ; FANG YUJIAO ; J.THOMPSON GARTH ; CHEN GAO ; ZHANG XIAOTONG
Author Information

1. Department of Neurosurgery,the Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310009,China
2. Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological Diseases,Hangzhou 310009,China
3. MOE Frontier Science Center for Brain Science and Brain-machine Integration,Zhejiang University,Hangzhou 310058,China
Keywords: Energy metabolism; Magnetic resonance imaging(MRI); Magnetic resonance spectroscopy(MRS); Multi-nuclear; Radiofrequency coil; Three-dimensional(3D)printing
From: Journal of Zhejiang University. Science. B 2024;25(2):168-180,后插1-后插4
CountryChina
Language:Chinese
Abstract: Energy metabolism is fundamental for life.It encompasses the utilization of carbohydrates,lipids,and proteins for internal processes,while aberrant energy metabolism is implicated in many diseases.In the present study,using three-dimensional(3D)printing from polycarbonate via fused deposition modeling,we propose a multi-nuclear radiofrequency(RF)coil design with integrated 1H birdcage and interchangeable X-nuclei(2H,13C,23Na,and 31P)single-loop coils for magnetic resonance imaging(MRI)/magnetic resonance spectroscopy(MRS).The single-loop coil for each nucleus attaches to an arc bracket that slides unrestrictedly along the birdcage coil inner surface,enabling convenient switching among various nuclei and animal handling.Compared to a commercial 1H birdcage coil,the proposed 1H birdcage coil exhibited superior signal-excitation homogeneity and imaging signal-to-noise ratio(SNR).For X-nuclei study,prominent peaks in spectroscopy for phantom solutions showed excellent SNR,and the static and dynamic peaks of in vivo spectroscopy validated the efficacy of the coil design in structural imaging and energy metabolism detection simultaneously.