Review: Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies
- Author:
Shi-Ping LUH
1
;
Chi-Huei CHIANG
Author Information
1. Chung-Shan Medical University Hospital
- Keywords:
Acute lung injury;
Acute respiratory distress syndrome;
Ventilator;
Cell therapy
- From:
Journal of Zhejiang University. Science. B
2007;8(1):60-69
- CountryChina
- Language:Chinese
-
Abstract:
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), which manifests as non-cardiogenic pulmonary edema, respiratory distress and hypoxemia, could be resulted from various processes that directly or indirectly injure the lung.Extensive investigations in experimental models and humans with ALI/ARDS have revealed many molecular mechanisms that offer therapeutic opportunities for cell or gene therapy. Herein the present strategies and future perspectives of the treatment for ALI/ARDS, include the ventilatory, pharmacological, as well as cell therapies.
