Effects of two medicinal plants Psidium guajava L. (Myrtaceae) and Diospyros mespiliformis L. (Ebenaceae) leaf extracts on rat skeletal muscle cells in primary culture
- Author:
R.G BELEMTOUGRI
1
;
B CONSTANTIN
;
C COGNARD
;
G RAYMOND
;
L SAWADOGO
Author Information
1. University of Ouagadougou
- Keywords:
Psidium guajava;
Diospyros mespiliformis;
Myrtaceae;
Ebenaceae;
Medicinal plants;
Intracellular calcium;
Sarcoplasmic reticulum;
Caffeine
- From:
Journal of Zhejiang University. Science. B
2006;7(1):56-63
- CountryChina
- Language:Chinese
-
Abstract:
Crude decoction, aqueous and ethanolic extracts of two medicinal plants (Psidium guajava and Diospyros mespiliformis), widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for their antagonistic effects on caffeine induced calcium release from sarcoplasmic reticulum of rat skeletal muscle cells. These different extracts showed a decrease of caffeine induced calcium release in a dose dependent manner. Comparison of the results showed that Psidium guajava leaf extracts are more active than extracts ofDiospyros mespiliformis and that crude decoctions show better inhibitory activity.The observed results could explaine their use as antihypertensive and antidiarrhoeal agents in traditional medicine, by inhibiting intracellular calcium release.
