Development and validation of a simplified height?specific blood pressure cutoffs table for screening hypertension in Chinese children and adolescents
10.3760/cma.j.issn.0253?9624.2019.07.009
- VernacularTitle:儿童青少年身高别高血压筛查界值简化表的制定与验证
- Author:
Yaping HOU
1
;
Qin LIU
;
Liu YANG
;
Min ZHAO
;
Xinnan ZONG
;
Bo XI
Author Information
1. 山东大学公共卫生学院流行病学系 山东大学儿童心血管研究中心
- Keywords:
Hypertension;
Child;
Adolescent;
Cross?sectional studies;
Cut?offs
- From:
Chinese Journal of Preventive Medicine
2019;53(7):701-705
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop and validate a simplified height?specific blood pressure cutoffs table for screening hypertension in Chinese children and adolescents. Methods We developed a simplified height?specific blood pressure cut offs table according to Chinese Blood Pressure Reference for Children and Adolescents aged 7-18 years (WS/T 610?2018) (hereafter referred to as "complex definition"). Populations from Early Warning, Diagnosis and Treatment of Children Cardiovascular Disease Project ("Ji′nan sample") and Shandong Children Cardiovascular Cohort Study Project ("Zibo sample") were used as validation populations for evaluating the screening effect of the simplified table for elevated blood pressure and hypertension in children and adolescents. Results We developed simplified height?specific blood pressure cutoffs table including 7 height groups and 28 cutoffs. Both Ji′nan and Zibo samples were selected by convenient sampling method, and the former included 7 233 participants aged 7 to 17 years, among whom 3 790 (52.4%) were boys. Latter population included 1 277 participants aged 7 to 11 years, among whom 681 (53.3%) were boys. The simplified table performed well for identifying elevated blood pressure in Ji′nan sample, with values of area under the receiver operating curve (AUC) (95%CI), sensitivity, specificity, and Kappa statistic as 0.96 (0.95-0.97), 93.0%, 98.5% and 0.91, respectively, which were similar with results in Zibo sample [the values were 0.92 (0.90-0.95), 87.0%, 98.0% and 0.85, respectively]. The simplified table also performed well for identifying hypertension in Ji′nan sample with values of AUC (95%CI), sensitivity, specificity, and Kappa statistic as 0.92 (0.91-0.94), 86.9%, 98.1% and 0.85, respectively, which were similar with results in Zibo sample [the values were 0.94 (0.91-0.96), 88.2%, 98.9% and 0.88, respectively]. Conclusion Screening for elevated and high blood pressure based on simplified height?specific blood pressure cutoffs table is easy to use and it shows satisfying effect.
