Research progress of interaction models between intestinal microflora and host cells
10.3760/cma.j.issn.0253?9624.2019.06.019
- VernacularTitle:肠道菌群与宿主细胞相互作用模型研究进展
- Author:
Junkui CHEN
1
;
Huahai CHEN
;
Xin WANG
;
Yeshi YIN
Author Information
1. 浙江师范大学化学与生命科学学院
- Keywords:
Intestinal microbes;
Intestinal epithelial cells;
Interaction models between intestinal microflora and host cells
- From:
Chinese Journal of Preventive Medicine
2019;53(6):638-644
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal microbes play an important role in human health. The development of various clinical diseases, such as obesity, diabetes and cardiovascular disease, is closely related to the imbalance of intestinal microflora. With the development of high?throughput sequencing technology, there has been a breakthrough in the understanding of intestinal microorganism. The interaction between intestinal epithelial cells and intestinal microbes has become one of the hotspots and difficulties of current research. Because of the constraints of ethical review and experimental cost, people are more interested in the development of interaction models between the intestinal microflora and the host cells. In this paper, interaction models between intestinal microflora and host cells, and its working principle and application prospect are reviewed, hoping to provide new techniques and new ideas for studying functions of intestinal microbes.
