The role of Sabin inactivated poliovirus vaccine in the final phase of global polio eradication
10.3760/cma.j.issn.0253-9624.2016.12.003
- VernacularTitle:Sabin株脊髓灰质炎灭活疫苗在全球消灭脊髓灰质炎最后阶段的作用
- Author:
Shaozhong DONG
1
;
Wenbing ZHU
Author Information
1. 中国医学科学院北京协和医学院医学生物学研究所
- Keywords:
Poliomyelitis;
Vaccines,inactivated;
Endgame strategic plan
- From:
Chinese Journal of Preventive Medicine
2016;50(12):1032-1035
- CountryChina
- Language:Chinese
-
Abstract:
Global polio eradication has entered its final phase, but still faces enormous challenges. The Polio Eradication and Endgame Strategic Plan (2013-2018) set the target for making the world polio-free by 2018. Meanwhile, the World Heath Organization Global Action Plan (GAP Ⅲ) recommended that polioviruses be stored under strict conditions after eradication of the wild poliovirus. At least one dose of inactivated poliovirus vaccine (IPV) would be required for each newborn baby in the world to ensure successful completion of the final strategy and GAPⅢ. The Sabin IPV has a high production safety and low production cost, compared with the wild-virus IPV and, therefore, can play an important role in the final stage of global polio eradication.