Serum Angiotensin-Coverting Enzyme Levels in Coal Worker's Pneumoconiosis.
10.12701/yujm.1989.6.1.109
- Author:
Kyung Dong KIM
;
Myung Sook CHOI
;
Chae Hoon LEE
;
Chung Sook KIM
;
Eun Kyung BAE
- Publication Type:Original Article
- MeSH:
Anthracosis*;
Coal*;
Fasting;
Follow-Up Studies;
Humans;
Methods
- From:Yeungnam University Journal of Medicine
1989;6(1):109-119
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We measured fasting Serum Angiotensin-Converting Enzyme (SACE) in 100 healthy controls and 75 coal worker's pneumoconiosis (CWP) patients by a commercial kits (ACEcolor®, Fujirio Inc., Japan) and evaluated this manual method. The linear range extends to an activity of 80U/L. Precision on a commercial control serum (ACE control-N®, Sigma Co.) with a mean value of 9.47U/L yielded a within-run and between-run CVs are 5.6% (N=15) and 6.9% (N=14) respectively. Save in 75 CWP was 20.3±5.7U/L (mean±s.d.); higher than in healthy controls (13.4±3.9U/L, P<0.01). No correlation was found between SACE, sex, and age. The results suggest that the measurement for SACE and follow-up SACE in coal workers may be a useful diagnostic tools for CWP.
