Advances in non-carcinogenic toxicity of trichloroethylene
10.3760/cma.j.issn.0253-9624.2015.09.016
- VernacularTitle:三氯乙烯非致癌性毒性研究进展
- Author:
Peiwu HUANG
1
;
Xuan LI
;
Wei LIU
;
Jianjun LIU
Author Information
1. 518055深圳市疾病预防控制中心现代毒理学重点实验室
- Keywords:
Trichloroethylene;
Occupational exposure;
Toxic effect;
Epidemiological study;
Mechanism research
- From:
Chinese Journal of Preventive Medicine
2015;(9):844-848
- CountryChina
- Language:Chinese
-
Abstract:
Trichloroethylene (TCE) is a widely used organic solvent and an important industrial material.Due to mass production and use,and improper waste disposal, TCE has become a common environmental contaminant, so there is a wide range of occupationally and environmentally exposed population.Occupational and environmental exposure to TCE can produce toxic effects on multiple organs and systems.This paper is a review of the immunotoxicity, reproductive toxicity, neurotoxicity, teratogenic effect and other non-carcinogenic toxic effects of TCE from the aspects of epidemiological study, experimental evidence on animals and toxic mechanisms.