Distribution of manganese,cobalt and molybdenum in blood and urine among general population in 8 provinces of China
10.3760/cma.j.issn.0253-9624.2014.09.008
- VernacularTitle:中国八省份一般人群血和尿中锰、钴、钼水平分布的研究
- Author:
Yajuan PAN
1
;
Chunguang DING
;
Aihua ZHANG
;
Banghua WU
;
Hanlin HUANG
;
Chun ZHU
;
Deye LIU
;
Baoli ZHU
;
Guang XU
;
Hua SHAO
;
Shanzhuo PENG
;
Xianlong JIANG
;
Chunxiang ZHAO
;
Changcheng HAN
;
Hongrong JI
;
Shanfa YU
;
Xiaoxi ZHANG
;
Longlian ZHANG
;
Yuxin ZHENG
;
Huifang YAN
Author Information
1. 中国疾病预防控制中心职业卫生与中毒控制所 化学安全与健康重点实验室
- Keywords:
Manganese;
Cobalt;
Molybdenum;
Blood;
Urine;
Inductive coupled plasma mass spectrometry
- From:
Chinese Journal of Preventive Medicine
2014;(9):784-790
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluated the manganese (Mn), cobalt (Co) and molybdenum (Mo) levels in blood and urine among general population in China , and thereby to analyze their prevalent features.Methods From 2009 to 2010, a total of 18 120 subjects of general population aged 6-60 years were recruited from 24 districts in 8 provinces in eastern , central and western China mainland , by cluster random sampling method.The information about their living environment and health status were collected by questionnaire , and their blood and urine samples were also collected.Inductive coupled plasma mass spectrometry ( ICP-MS) was applied to test the Mn , Co and Mo levels of blood and urine samples , and the Mn, Co, Mo distribution in blood and urine among groups of population in different ages and genders were then analyzed.Results Among general population in China , the geometric mean ( GM) of Mn concentration in blood was 8.98 μg/L.The Mn concentration in blood among males and females were separately 8.14 μg/L and 9.88 μg/L ( Z =-18.84, P <0.01 ).The GM of Mn concentration in urine was 0.63 μg/L.The Mn concentration in urine among males and females were separately 0.62 μg/L and 0.63 μg/L ( Z =-0.67, P >0.05 ).The geometric mean ( GM ) of Co concentration in blood was 0.194 μg/L.The Co concentration in blood among males and females were separately 0.166 μg/L and 0.225 μg/L ( Z =-23.04, P <0.01 ).The GM of Co concentration in urine was 0.282 μg/L.The Co concentration in urine among males and females were separately 0.260μg/L and 0.307μg/L ( Z=-7.35, P<0.01).The GM of Mo concentration in blood was 0.25μg/L.The Mo concentration in blood among male and female group were separately 0.27 μg/L and 0.23 μg/L ( Z =-5.03, P <0.01 ).The GM of Mo concentration in urine was 27.7 μg/L.The Mo concentration in urine among males and females were 29.8 μg/L and 25.6μg/L (Z=-6.31,P<0.01), respectively.Conclusion The Mn, Co and Mo levels in blood and urine varied by gender and area among general population in China , the study provided basic data evidence for the following Mn , Co and Mo biological monitoring studies in near future.
