Current status of local treatment for multifocal / multicentric breast cancer
10.3760/cma.j.cn112139-20230723-00024
- VernacularTitle:多灶性/多中心性乳腺癌局部治疗的现状
- Author:
Xin LYU
1
;
Zhigang FAN
;
Yuntao LI
Author Information
1. 河北医科大学第四医院乳腺中心，石家庄 050011
- Keywords:
Breast neoplasms;
Mastectomy;
Multifocal/multicentricbreast cancer;
Breast conserving surgery;
Adjuvant radiotherapy
- From:
Chinese Journal of Surgery
2024;62(2):172-176
- CountryChina
- Language:Chinese
-
Abstract:
The detection rate of multifocal / multicentric breast cancer (MMBC) is increasing, and the local treatment of MMBC is attracting more attention. Relevant research focuses on the selection of surgical methods, the application of radiotherapy, and the feasibility of local ablation. Currently, due to the high rate of local recurrence in breast conserving surgery, most Chinese doctors recommend mastectomy to patients with MMBC. Recent studies have shown that with the development of imaging technology, surgical techniques, accurate judgment of the resection margin, the emergence of new therapeutic drugs and the improvement of the accuracy of radiotherapy, for eligible patients with MMBC, breast conserving surgery did not increase the local recurrence rate while ensuring negative margin and cosmetic results. Whether patients with MMBC must receive adjuvant radiotherapy after mastectomy is controversial, with some evidence suggesting that MMBC may increase the risk of local recurrence and should be an important consideration for radiotherapy, and there is also evidence that the local recurrence rate of MMBC was higher regardless of the type of surgery. In general, the local treatment modality for MMBC is essentially the same as that for unifocal breast cancer, but more prospective studies are needed for further evaluation.
