Progress in targeting gene therapy
10.3760/j.issn:1003-9406.2001.01.017
- VernacularTitle:靶向基因治疗的研究进展
- Author:
Xingjiang XIE
1
;
Ling TIAN
;
Yuquan WEI
Author Information
1. the First Affiliated Hospital West China University of Medical Sciences
- From:
Chinese Journal of Medical Genetics
2001;18(1):59-61
- CountryChina
- Language:Chinese
-
Abstract:
In recent years the research on targeting in gene therapy has made much exciting progress. Many new technologies show great promising prospects such as the delivery of therapeutic gene to targeted cells by some antibodies or ligands, the use of specific gene promoter to tightly control gene expression within disease microenviroment, the use of some orally taken drugs for regulating expression time and expression level of DNA, and the targeted correction of deleted or mutated gene using RNA/DNA oligonucleotides. Yet, researchers still have a long way to go in order to reach the goal of applying the targeting gene therapy in clinical practice.