Delayed Hemolytic Transfusion Reaction Caused by Anti-Jkb Antibody in a Renal Transplant Recipient.
- Author:
Seong Hyun SON
1
;
Byoung Yong SHIM
;
Hyun Jung JOO
;
Jung Hee PARK
;
Byung Soo KIM
;
Joo Hyun PARK
;
Chul Woo YANG
;
Yong Soo KIM
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Delayed hemolytic transfusion reaction;
Renal transplantation;
Anti-Jkb Antibody
- MeSH:
Anemia;
Anemia, Hemolytic;
Blood Group Incompatibility*;
Female;
Humans;
Kidney Transplantation;
Mass Screening;
Middle Aged;
Plasmapheresis;
Renal Dialysis;
Thorax;
Transplantation*
- From:Korean Journal of Nephrology
1999;18(3):501-504
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of 46-year-old women who suffered from delayed transfusion hemolytic anemia due to anti-Jkb antibody after renal transplantation. The patient had been treated with hemodialysis and had a past history of multiple transfusion. On the second postoperative day, she received 2 units of packed red cell. During transfusion, she complained of mild chest tightness only, but 10 days later, anemia of unknown origin developed. Irregular antibody was found in her serum and identified as anti- Jkb antibody. Together with other serologic findings, she was diagnosed as delayed hemolytic transfusion reaction due to anti -Jkb antibody. We thought that this reaction might be the amnestic response to previous exposure during delivery or remote multiple transfusion. Our patient responded to steroid and plasmapheresis and recovered without severe hemolytic transfusion reaction. In conclusion, antibody screening tests and identification test might be considered as a routine pretransfusion test for all renal recipients for safe transfusion practices.
