The effect of adjuvant radiotherapy on postoperative complications of immediate deep inferior epigastric artery perforator flap breast reconstruction
10.3760/cma.j.cn112139-20201103-00781
- VernacularTitle:辅助放疗对乳腺癌患者即刻腹壁下动脉穿支皮瓣乳房重建手术后并发症的影响
- Author:
Yingying ZHANG
1
;
Xiaoli YU
;
Ayong CAO
;
Zhen HU
;
Guangyu LIU
;
Zhenzhou SHEN
;
Zhimin SHAO
;
Jiong WU
Author Information
1. 复旦大学附属肿瘤医院乳腺外科 复旦大学上海医学院肿瘤学系 200032
- Keywords:
Breast neoplasms;
Mammaplasty;
Surgical flaps;
Radiotherapy;
Fat necrosis
- From:
Chinese Journal of Surgery
2021;59(9):777-781
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the effect of adjuvant radiotherapy on postoperative complications of immediate deep inferior epigastric artery perforator (DIEP) flap breast reconstruction.Methods:Data was collected from 185 patients underwent immediate DIEP reconstruction during November 2006 to March 2020 Department of Breast Surgery, Fudan University Shanghai Cancer Center. All the patients were female, aging (43.0±7.8) years (range: 29 to 61 years). The series included with a total of 187 flaps (2 bilateral, 183 unilateral). Included patients were divided into 2 groups: immediate DIEP reconstruction requring or not requring post-mastectomy radiation therapy (71 cases (71 flaps) in PMRT group, 114 cases (116 flaps) in control group). The aesthetic outcome were measured by Kroll score system and compared between the groups by t test. The complications included partial flap loss, minor necrosis were analyzed between the groups by χ 2 test, while the influence of the other correlation factors on complication occurrence was analyzed by Logistic analysis. Results:The controll groups showed better aesthetic results (2.21±0.55 vs. 2.47±0.82, t=-2.593, P=0.010). Complication rate in PMRT group was higher than that in control group (19.7% (15/71) vs. 4.2% (4/116), χ2=15.079, P<0.01). The complication rate was not correlated with age, body mass index, perforator number, neoadjuvant chemotherapy and adjuvant chemotherapy. Conclusions:Correlation was observed between adjuvant radiotherapy and post-operative complication of the DIEP flap. However, the complication occurrence and aesthetic results remain in the acceptable range. The other factors such as age, body mass index, perforator number, neoadjuvant chemotherapy and adjuvant chemotherapy should not be considered as prognosis factor of post-operative complication of the DIEP flap.
