Application Progress of Resting-State Functional Magnetic Resonance Imaging in Study of Default Mode Network in Patients with Vascular Cognitive Impairment

VernacularTitle:静息态功能磁共振成像在血管性认知障碍患者默认网络研究中的应用进展
Author: Xue WANG ¹ ; Yali NIU ; Jing WANG ; Xiaona CHEN ; Chunxiao WAN
Author Information

1. 天津医科大学总医院康复医学科,天津市,300052
Keywords: resting-state functional magnetic resonance imaging; vascular cognitive impairment; default mode network
From: Chinese Journal of Medical Instrumentation 2024;48(1):51-56
CountryChina
Language:Chinese
Abstract: Vascular cognitive impairment(VCI)is a group of syndromes ranging from mild cognitive impairment to dementia caused by cerebrovascular disease,due to the lack of sensitivity and specific biomarkers,it is difficult to identify and diagnose early.Abnormal connectivity is observed in brain regions of patients with vascular cognitive disorders,locates mainly in the default mode network(DMN),and changes in their abnormal functional connectivity correlated with the degree of patients' cognitive impairment.Resting-state functional magnetic resonance imaging(rs-fMRI)is a commonly used method to detect the internal activity of the brain at resting state.The use of various rs-fMRI to study abnormal changes in the DMN in patients with VCI is useful to further investigate the pathogenesis of VCI and provide an objective basis for imaging.This article mainly reviews the application of rs-fMRI in the DMN in patients with VCI,bringing new perspectives for the correct diagnosis and assessment of VCI.