Research status of risk prediction and management of postoperative pancreatic fistula
10.3760/cma.j.cn112139-20200404-00283
- VernacularTitle:胰腺术后胰瘘的风险预测及处理的研究现状
- Author:
Ruizhe ZHU
1
;
Zhe CAO
;
Wenhao LUO
;
Taiping ZHANG
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院基本外科 疑难重症及罕见病国家重点实验室 100730
- Keywords:
Pancreatic fistula;
Postoperative complications;
Risk prediction;
Grading criteria
- From:
Chinese Journal of Surgery
2021;59(4):311-315
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic fistula is a common complication of pancreatic surgery and also a leading cause of postoperative death. The 2016 International Study Group on Pancreatic Surgery definition and grading criterion of postoperative pancreatic fistula (POPF) is instructive to clinical practice and scientific research. Although the criterion is widely applied, further optimization is required. It has established a variety of risk prediction models, which forwards the early diagnosis of POPF. However, the inconsistency of the criteria and the potential mutual influence of multiple factors hindered the model extrapolation. Moreover, it remains controversial in specific strategies of perioperative nutritional support, surgical methods, postoperative drainage, and somatostatin application in the prevention and treatment of POPF. Thus, more prospective studies are needed to explore safer, more effective and economical POPF prediction and intervention methods.
