The change in nutritional status of pancreatic cancer patients undergoing neoadjuvant therapy and its influence on these patients′ postoperative outcomes as well as prognosis
10.3760/cma.j.cn112139-20191219-00630
- VernacularTitle:胰腺癌患者新辅助治疗前后营养状况的改变及其对术后结局和预后的影响
- Author:
Zhangping YU
1
;
Wei CHEN
;
Menghua DAI
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院基本外科 100730
- Keywords:
Pancreatic neoplasms;
Nutritional support;
Neoadjuvant therapy;
Postoperative complication;
Prognosis
- From:
Chinese Journal of Surgery
2020;58(10):754-757
- CountryChina
- Language:Chinese
-
Abstract:
Neoadjuvant therapy has been one of the standard therapies for borderline resectable pancreatic cancer and locally advanced pancreatic cancer, but it may deteriorate these patients′ nutritional status while controlling the progress of cancer, which inevitably influences these patients′ postoperative outcomes and prognosis.In this article, we tried to answer this problem by reviewing other studies.And we found that neoadjuvant therapy would influence patients′ postoperative outcomes and prognosis by deteriorating their nutritional status.But effective nutritional support can prevent it.It indicates that there is a need for these patients to receive nutritional support as soon as possible.However, in consideration of the limited number of relevant studies and their limitations, there is a need for more studies with strict design to answer this problem.And it can provide evidence for early nutritional support in pancreatic cancer patients who is going to undergo neoadjuvant therapy.
