A Drug Delivery Device for Drug-eluting Stents Simulating the Cardiovascular Blood Flow Pattern
10.3969/j.issn.1671-7104.2016.05.003
- VernacularTitle:一种模拟心脏血流形态的药物洗脱支架的药物释放装置
- Author:
Tianping YAO
1
;
Fengping ZOU
;
Wentao YAN
;
Jiahua HUANG
Author Information
1. 上海市医疗器械检测所
- Keywords:
simulating dissolution device;
drug-eluting stent;
rapamycin
- From:
Chinese Journal of Medical Instrumentation
2016;40(5):322-325
- CountryChina
- Language:Chinese
-
Abstract:
A novel drug delivery device simulating the cardiovascular bloodfl ow pattern was introduced. The device was used to simulate the in vivo drug release in the drug-eluting stents. The results regarding the drug release rate were subject to the pattern from in vivo measurement. Therefore, the device was validated as a measurement method for in vivo drug release rate.