The Erythrocyte Deformability Measuring System Based on Microlfuidic and Machine Vision
10.3969/j.issn.1671-7104.2016.03.005
- VernacularTitle:基于微流控和机器视觉的红细胞变形性测量系统
- Author:
Jianxun HOU
1
;
Sehyun SHIN
Author Information
1. 深圳市药品检验研究院 深圳市医疗器械检测中心
- Keywords:
erythrocyte;
deformability;
microfluidic;
machine vision
- From:
Chinese Journal of Medical Instrumentation
2016;40(3):173-175
- CountryChina
- Language:Chinese
-
Abstract:
The erythrocyte deformability mainly depends on the composition of the membrane and cytoplasm, which consist of hemoglobin and other constituents. The most of current devices to measure erythrocyte deformability require washing process after the measurement which is labor-intensive and time-consuming. This article introduces an improved measuring system based on microfluidic and machine vision (RSD) which adopts disposable microfluidic channel and conventional laser-diffraction technique to determine erythrocyte deformability. To validate the accuracy and repeatability of RSD, several experiments are conducted to determine deformability of normal erythrocytes measured by RSD and a conventional ektacytometer(LORCA). The measured Elongation Index (EI) by RSD, which is a parameter directly related to erythrocyte deformability, is in excel ent agreement with it measured by LORCA.
