Nanobody：a Novel Molecular Imaging Tool
10.3969/j.issn.1671-7104.2015.06.010
- VernacularTitle:纳米抗体：一种新型的分子成像工具
- Author:
Weidang LIU
1
;
Weifeng LIU
Author Information
1. 上海中医药大学附属岳阳中西医结合医院医学装备处
- Keywords:
nanobody;
diagnosis and detection;
molecular imaging;
cancer
- From:
Chinese Journal of Medical Instrumentation
2015;(6):423-426
- CountryChina
- Language:Chinese
-
Abstract:
Nanobodies are derived from the variable domain of the heavy-chain antibodies (HCAbs) that occur naturaly in the serum of camels. Using nanobody-based probes, several imaging techniques such as radionuclide-based, optical and ultrasound have been employed for visualization of target expression in various disease models. Combined with application and clinical data of nanobody in molecular imaging in recent years, this paper introduces its application in the diagnosis of diseases and the future development as a novel molecular imaging tool.
