Toxic epidermal necrolysis induced by deflazacort.
10.4168/aard.2016.4.3.221
- Author:
Dail YOUN
1
;
Min Hye KIM
;
Seok Woong KOH
;
Jung Won KIM
;
Sang Eun YOON
;
Hyeon Kyeong JEON
;
Young Joo CHO
Author Information
1. Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea. yjcho@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Stevens-Johnson syndrome;
Nephrotic syndrome;
Drug hypersensitivity syndrome
- MeSH:
Adrenal Cortex Hormones;
Adult;
Dexamethasone;
Drug Hypersensitivity Syndrome;
Eating;
Exanthema;
Humans;
Immunoglobulins;
Mortality;
Nephrotic Syndrome;
Skin;
Steroids;
Stevens-Johnson Syndrome*
- From:Allergy, Asthma & Respiratory Disease
2016;4(3):221-224
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions to drugs, which carry significant morbidities and mortalities. Although SJS and TEN can be treated by corticosteroids or intravenous immunoglobulin, they may be induced by steroids. We experienced a 36-year-old man who developed whole body erythromatous maculopapular rashes and multiple bullae after ingestion of deflazacort. After avoidance of deflazacort and use of dexamethasone, skin lesions resorbed. We reported a case of TEN diagnosed by characteristic clinical findings with a brief review of the literature.
