Lipid metabolism of adipocytes and macrophages after fat grafting
10.3760/cma.j.cn114453-20231025-00132
- VernacularTitle:脂肪移植后脂肪细胞和巨噬细胞的脂质代谢
- Author:
Shujie XU
1
;
Jianhua GAO
;
Xingtang NIU
;
Yi YUAN
Author Information
1. 南方医科大学南方医院整形外科，广州 510515
- Keywords:
Adipose tissue;
Fat grafting;
Lipid metabolism;
Adipocyte;
Macrophage;
Oil cyst
- From:
Chinese Journal of Plastic Surgery
2024;40(7):787-795
- CountryChina
- Language:Chinese
-
Abstract:
The survival rate of fat grafts is challenging to predict, and related complications such as oil cyst formation and fat necrosis may occur. The primary cause is that adipocytes are destroyed during fat grafting, and adipocyte necrosis releases a large number of oil droplets. Understanding the lipid metabolism of fat grafts, including intracellular lipid metabolism and extracellular oil droplet metabolism, is crucial to improve the survival rate of fat grafts and reduce complications. This article primarily explored the lipid metabolism and associated immune regulation of adipocytes and macrophages under both physiological and inflammatory conditions after fat grafting, and explained the mutual regulatory relationship between fat graft metabolism and the host’s overall lipid metabolism.
