Effect of macroglossia reduction combined with radiofrequency ablation in the treatment of Beckwith-Wiedemann syndrome with giant tongue
10.3760/cma.j.cn114453-20231009-00069
- VernacularTitle:舌缩小矫形联合射频消融术在Beckwith-Wiedemann综合征巨舌治疗中的效果观察
- Author:
Yufeng GUO
1
;
Xingqiang GAO
;
Chenbin DONG
Author Information
1. 复旦大学附属儿科医院厦门医院 厦门市儿童医院耳鼻咽喉头颈外科，厦门 361006
- Keywords:
Beckwith-Wiedemann syndrome;
Macroglossia;
Glossoplasty;
Radiofrequency ablation;
Surgical operation
- From:
Chinese Journal of Plastic Surgery
2024;40(7):747-754
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aims to summarize the surgical efficacy of macroglossia reduction combined with radiofrequency ablation of Beckwith-Wiedemann Syndrome (BWS).Methods:A retrospective analysis was conducted on the clinical data of patients with macroglossia who received treatment at the Department of Otolaryngology-Head and Neck Surgery, Xiamen Children’s Hospital between May 2019 and July 2022. All patients with macroglossia underwent either one-stage or staged anterior tongue V-shaped incision massive resection, followed by needle tip low-temperature plasma radiofrequency ablation on the lateral and base of the tongue. The postoperative complications in pediatric patients were monitored, including the incision shape of the tongue body, restoration of tongue body structure and function. MRI scans of the tongue were performed at 3 and 12 months post-operation to evaluate tissue healing, changes in tongue volume, and whether there was successful retraction of the enlarged tongue into the oral cavity for evaluating treatment efficacy (cured or not cured).Results:The study included 70 cases, comprising 31 male and 39 female patients, with an average age of 15.4 months (ranging from 5 months to 4 years old). Among them, 68 cases underwent macroglossia reduction combined with radiofrequency ablation at the same time, and 2 cases underwent macroglossia reduction surgery first in other hospitals, and tongue body radiofrequency ablation was performed one year after the surgery. All children were followed up foran average follow-up time of 18 months (6 to 36 months). There were no serious complications such as massive hemorrhage and tongue hematoma. After the operation, 14 cases of superficial rupture of tongue tip wound were gradually improved after 5-7 days of no oral eating, and recovered after 4-12 weeks of liquid diet. Thirteen cases had suture reactions in the tongue back, which were self-resolving within 2 to 3 weeks with no special treatment. All patients showed significant reduction in tongue size after the surgery, which could be completely inserted into the oral cavity, and the treatment effect was satisfactory.Conclusion:Macroglossia reduction combined with radiofrequency ablation is a feasible and effective method for the treatment of BWS with macroglossia and is recommended for application.
