A Case of Long-Term Complete Remission of Advanced Gastric Adenocarcinoma with Liver Metastasis.
10.5230/jgc.2016.16.2.115
- Author:
Ch'angbum RIM
1
;
Jung Ae LEE
;
Soojung GONG
;
Dong Wook KANG
;
Heebum YANG
;
Hyun Young HAN
;
Nae Yu KIM
Author Information
1. Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea. naeyu46@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Gastric cancer;
Liver metastasis;
Gastrectomy, S-1, Cisplatin;
Cisplatin
- MeSH:
Adenocarcinoma*;
Biopsy;
Cisplatin;
Deglutition;
Drug Therapy;
Drug Therapy, Combination;
Dyspepsia;
Esophagus;
Gastrectomy;
Humans;
Liver*;
Lymph Node Excision;
Middle Aged;
Neoplasm Metastasis*;
Splenectomy;
Stomach Neoplasms
- From:Journal of Gastric Cancer
2016;16(2):115-119
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report the case of a patient with gastric adenocarcinoma with multiple liver metastases. This patient showed complete remission for more than 68 months after S-1/cisplatin combination chemotherapy and radical total gastrectomy. The patient, a 63-year-old man, presented with dyspepsia and difficulty in swallowing. Endoscopic findings showed a huge ulcero-infiltrative mass at the lesser curvature of the mid-body, extending to the distal esophagus. Biopsy revealed a poorly differentiated tubular adenocarcinoma. An abdominal computed tomography scan demonstrated multiple hepatic metastases. S-1/cisplatin combination chemotherapy was initiated, and following completion of six cycles of chemotherapy, the gastric masses and hepatic metastatic lesions had disappeared on abdominal computed tomography. Radical total gastrectomy and D2 lymphadenectomy combined with splenectomy were performed. The patient underwent three cycles of S-1/cisplatin combination chemotherapy followed by tegafur-uracil therapy for 1 year. He remained in complete remission for more than 68 months after surgery.
