Application and progress of adipose-derived stem cells in peripheral nerve injury repair
10.3760/cma.j.cn114453-20231023-00105
- VernacularTitle:脂肪干细胞在周围神经损伤修复中的应用及进展
- Author:
Jiancong LIANG
1
;
Ziqing DONG
Author Information
1. 南方医科大学南方医院整形外科,广州 510515
- Keywords:
Adipose-derived stem cells;
Tissue engineering;
Peripheral nerve;
Nerve injury;
Nerve regeneration
- From:
Chinese Journal of Plastic Surgery
2024;40(3):337-342
- CountryChina
- Language:Chinese
-
Abstract:
Peripheral nerve injury is a common clinical disease. Traditional treatments include drug therapy, microsurgery and autologous nerve transplantation. Drug therapy is not effective due to the poor con-centration of local drugs. Surgical method are limited by the length of the nerve defect and the lack of nerve donor sites. In addition, surgery is still tissue repair. With the progress of tissue engineering and stem cell research, tissue engineering combined with stem cells for nerve regeneration and repair has become a current research hotspot. Therefore, this paper reviews the process of peripheral nerve repair after injury, the mechanism and the progress of peripheral nerve repair based on adipose stem cells in the past five years.