The effect of sex hormone on adolescent bone growth in patients with disorders of sexual development
10.3760/cma.j.cn114453-20231022-00093
- VernacularTitle:性激素对性发育异常患者青春期骨骼生长的影响
- Author:
Zhiwan LIU
1
;
Xiang JIE
;
Wenjun ZHANG
;
Antang LIU
;
Lie ZHU
;
Xiaohai ZHU
;
Zheyuan HU
Author Information
1. 海军军医大学第二附属医院烧伤、整形外科，上海 200003
- Keywords:
Puberty;
Body height;
Sex hormone;
Disorders of sexual development
- From:
Chinese Journal of Plastic Surgery
2024;40(3):331-336
- CountryChina
- Language:Chinese
-
Abstract:
The growth of puberty height is affected by many factors, among which the role of sex hormones is particularly important. The height increase in puberty accounts for about 20% of the final height in adulthood. It was previously believed that the final height of patients with disorders of sexual development was impaired due to the disorder of sex hormones. However, there are more classifications and subtypes of disorders of sexual development, and the growth patterns of patients with different subtypes of disorders of sexual development are also different. This article briefly reviews puberty bone growth, the effect of sex hormones on puberty bones, the sex hormone spectrum and growth pattern of patients with common disorders of sexual development, and the effect of growth hormone therapy.
