Analysis the Cupric Ion Release Characteristics of Different Copper Raw Materials in Intrauterine Device in Vitro Using ICP Method
10.3969/j.issn.1671-7104.2014.03.016
- VernacularTitle:运用ICP法分析宫内节育器用铜原材料的体外铜离子释放特性
- Author:
Hua LU
1
;
Tingting DING
;
Tianping YAO
;
Jiao SUN
Author Information
1. 上海交通大学医学院附属第九人民医院
- Keywords:
copper raw materials in Cu-containing Intrauterine device;
simulated uterine solution;
cupric ion release;
inductively coupled plasma(ICP)
- From:
Chinese Journal of Medical Instrumentation
2014;(3):216-218
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the Cupric ion release characteristics of dif erent copper raw materials in intrauterine device in vitro by ICP. Reveal the relationship between purity and shape of Cu-IUD copper and copper ion release. Methods According to a certain proportion, the copper raw materials were 100 times diluted into the simulated uterine solution at 37± 0.5 oC. Replaced medium at certain time points and col ected soaking liquid. Using ICP analyzed the concentration of copper ion released. Results The largest daily release of copper ions was in the first 7 days. There was no statistical y significant difference between the copper ion release amount of 99.99%and 99.95%purity copper wire ( P>0.05). The release of copper ion of the copper wire was far greater than that of the copper pipe in early stage (P<0.01).The release amount decreased and stabilized at 56 day. Conclusion Release characteristics of copper ion could effectively analysis by ICP. And in the same area, the release amount of copper ions of copper wire was greater than that of copper pipe.
