Research progress of botulinum toxin A in flap transplantation
10.3760/cma.j.cn114453-20210802-00329
- VernacularTitle:A型肉毒毒素在皮瓣移植中应用的研究进展
- Author:
Xianxi MENG
1
;
Xiancheng WANG
;
Yang SUN
;
Wenbo LI
Author Information
1. 中南大学湘雅二医院整形美容外科（烧伤科）, 长沙 410011
- Keywords:
Botulinum toxins;
Surgical flaps;
Blood supply;
Angiogenesis
- From:
Chinese Journal of Plastic Surgery
2023;39(9):1035-1038
- CountryChina
- Language:Chinese
-
Abstract:
Botulinum toxin A is of extensive application in medical cosmetology, such as wrinkle removal, facial lift, and improving the contour of face, shoulder, calf and so on. Recent studies have found that botulinum toxin A also plays a certain role in improving the blood supply of flaps. This paper reviews the relevant articles published in recent years, summarizes the application of botulinum toxin A in vivo and in vitro. The potential mechanism, for example, improving flap perfusion, reducing thrombogenesis, promoting angiogenesis and inhibiting inflammatory response are also analyzed in the paper. The successful application of botulinum toxin A can provide a more convenient and reliable method to improve the blood supply of the flap for clinical treatment, and that will make efforts to improve the prognosis of patients, shorten the hospitalization time and reduce the hospitalization expenses.
