A case of type A botulinum toxin injection poisoning treated with antitoxin
10.3760/cma.j.cn114453-20220315-00066
- VernacularTitle:抗毒素治疗A型肉毒毒素注射中毒1例
- Author:
Xuefei LIU
1
;
Yanglong ZHU
;
Liwen YANG
;
Hongyue LIAO
;
Peidong GAN
;
Yangyan YI
Author Information
1. 南昌大学第二附属医院医疗美容科，南昌 336000
- Keywords:
Botulinum toxins;
Poisoning;
Botulinum antitoxin
- From:
Chinese Journal of Plastic Surgery
2023;39(2):187-189
- CountryChina
- Language:Chinese
-
Abstract:
Botulinum toxin is a potent protein toxin produced by Clostridium botulinum. It acts directly on the brain nerve nucleus and peripheral neuromuscular junction, blocking the release of acetylcholine and thereby affecting nerve impulse transmission, ultimately leading to muscle paralysis. Mild cases may present with ocular muscle involvement, whereas severe cases may involve dysphagia, general paralysis, respiratory depression, and even death. This article reports on a patient who experienced severe poisoning symptoms after using type A botulinum toxin obtained through informal channels. The patient was treated with antitoxin on the 13th day after symptoms onset and achieved a significant improvement in their condition.
