A case of immune checkpoint inhibitor associated acute myocardial infarction
10.12025/j.issn.1008-6358.2024.20240466
- VernacularTitle:免疫检查点抑制剂相关急性心肌梗死病例分析
- Author:
Ran XU
1
;
Hao LU
;
Yan WANG
;
Leilei CHENG
Author Information
1. 复旦大学附属中山医院心内科,上海 200032
- Keywords:
immune checkpoint inhibitor;
acute myocardial infarction;
lung cancer
- From:
Chinese Journal of Clinical Medicine
2024;31(4):571-576
- CountryChina
- Language:Chinese
-
Abstract:
As an important advance in the treatment of anti-tumor therapy,immune checkpoint inhibitors significantly prolong the survival of patients with malignant tumors.At the same time,immune-related adverse reactions are also increasing,among which ICIs have increased the risk of acute coronary events,but clinical reports are rare.This paper analyzes the history of a patient with pulmonary small cell neuroendocrine carcinoma who developed acute myocardial infarction after ICIs treatment,suggesting that clinicians should be alert to the occurrence of ICIs-related acute myocardial infarction,and improve the prognosis of patients through early identification and intervention.