Feasibility of early treatment of congenital giant melanocytic nevus
10.3760/cma.j.cn114453-20220516-00147
- VernacularTitle:先天性巨大黑色素细胞痣早期治疗的可行性探讨
- Author:
Jiaqi ZHANG
1
;
Cheng CHEN
;
Fen SHI
;
Zheng SU
;
Xiaolian XIAO
;
Jian ZHANG
;
Chen CHEN
;
Yongzhen WANG
;
Weiqiang LIANG
;
Jinming ZHANG
Author Information
1. 中山大学孙逸仙纪念医院整形外科，广州 510000
- Keywords:
Tissue expansion;
Nevus, pigmented;
Orthopedics;
Surgical flaps;
Postoperative complications;
Congenital melanocytic nevus syndrome
- From:
Chinese Journal of Plastic Surgery
2022;38(11):1203-1209
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the feasibility of early treatment of congenital giant melanocytic nevus (CGMN).Methods:From October 2013 to December 2021, the clinical data of children with giant nevus treated with skin soft tissue expansion in the Plastic Surgery Department of Sun Yat-sen Memorial Hospital were analyzed retrospectively. A renal expander was implanted in the first stage, including single and repeated expansion. The giant nevus was removed and repaired in the second stage with an expanded skin flap. The occurrence of complications, such as wound infection, expander exposure, expander rupture, and flap congestion, were recorded. Children’s mental health problems and their parents’ satisfaction were also analyzed. The χ2 between children of different ages and the infection rate between children with an internal and external pot. Results:A total of 58 children, 24 males and 34 females, aged from 3 months to 3 years, with an average age of 1.45 years, were enrolled. A total of 190 expanders were implanted. The patients were followed for 5 to 106 months, averaging 42.43 months. In the first stage, 29 cases of wound infection, 41 cases of expander exposure, two cases of flap congestion, and 6 cases of expander rupture occurred. The flap transfers were not affected by these complications after appropriate treatment. The comparison of complication rates among 3 months~<1 year、1~<2 years、2~<3 years、3 years was 37.34%(31/83)、56.75% ((21/37) ), 33.33% (13/39) and 41.94%(13/31), respectively, No statistically significant difference ( χ2=5.21, P=0.157). The incidence of wound infection was 16.67% (6/36) and 14.94% (23/154), respectively, for the internal and external dilators. There was no significant difference in the location of the dilator pot and the incidence of wound infection ( χ2=0.07, P=0.795). The appearance of all children has been significantly improved. Thirty-nine children’s families are particularly satisfied, and 20 are generally satisfied with the treatment effect, and no mental health problems were found. Conclusions:Skin and soft tissue expansion is a reliable method for early treatment of congenital giant nevus.
