Comparisons of several formulations of botulinum toxin type A

VernacularTitle:几种A型肉毒毒素制剂的比较
Author: Donglei YU ¹ ; Guanzhong CHEN ; Hang WANG
Author Information

1. 四川大学华西口腔医院医疗美容科，成都　610041
Keywords: Botulinum toxin type A; Time of onset; Time of duration; Adverse events
From: Chinese Journal of Plastic Surgery 2022;38(7):839-845
CountryChina
Language:Chinese
Abstract: In 2020, two formulations of botulinum toxin type A (BoNT-A)named AbobotulinumtoxinA(Dysport ?) and LetibotulinumtoxinA(Letybo ?) have been officially approved by National Medical Products Administration to come on the market. To compare BoNT-As with different formulations, three BoNT-As[AbobotulinumtoxinA, OnabotulinumtoxinA(Botox ?), IncobotulinumtoxinA(Xeomin ?)] with relatively more clinical evidences internationally and two domestic BoNT-As[LanbotulinumtoxinA(Prosigne ?), LetibotulinumtoxinA] were included. Diffusion scale, conversion ratio, onset, duration and immunogenicity of different BoNT-As were reviewed in detail to provide reference for clinical practice.