The status of research and progress of tissue engineering technology in the treatment of lymphedema
10.3760/cma.j.cn114453-20200831-00482
- VernacularTitle:组织工程技术在淋巴水肿治疗的研究现状与进展
- Author:
Kuo CHEN
1
;
Pengwei LYU
;
Lan MU
Author Information
1. 郑州大学第一附属医院乳腺外科，郑州 450052
- Keywords:
Lymphedema;
Stem cells;
Tissue engineering;
Regenerative medicine;
Lymphatic regeneration
- From:
Chinese Journal of Plastic Surgery
2022;38(4):449-456
- CountryChina
- Language:Chinese
-
Abstract:
Lymphedema has a high incidence and lacks sustainable and effective treatment. Recently, with the development of tissue engineering and the popularization of interdisciplinary treatment, the lymphatic network can be reconstructed with lymphoid stem cell regenerative technology and tissue engineering technology combined with decellularized scaffolds. The treatment and prevention of lymphedema have recently achieved initial success in experiments. The long-term efficacy still needs to be verified by further investigations. The existing literature concerning treatment for lymphedema by stem cells and tissue engineering is critically presented and summarized in terms of the physiological characteristics of lymphatic vessels, pathological mechanism of lymphedema, application of stem cell technology in the treatment of lymphedema, and lymphatic tissue engineering. With the in-depth research on lymphatic regenerative medicine technology and lymphatic tissue engineering, the desire to successfully treat and prevent lymphedema through lymphatic regenerative medicine technology and tissue engineering can be realized.
