Tough choice of surgical treatment for duodenal gastrointestinal stromal tumor: pancreaticoduodenectomy or local resection?
10.3760/cma.j.cn.441530-20200615-00357
- VernacularTitle:十二指肠胃肠间质瘤外科治疗的艰难选择：胰十二指肠切除还是局部切除
- Author:
Haoran QIAN
1
;
Tianyu LIN
Author Information
1. 浙江大学医学院附属邵逸夫医院普通外科 浙江大学微创外科研究所，杭州 310016
- Keywords:
Gastrointestinal stromal tumor, duodenum;
Pancreaticoduodenectomy;
Local resection;
Imatinib
- From:
Chinese Journal of Gastrointestinal Surgery
2020;23(9):861-865
- CountryChina
- Language:Chinese
-
Abstract:
The therapeutic choice of duodenal gastrointestinal stromal tumor (GIST) has always been the focus of surgeons because of its special anatomy location. So far, surgery is the preferable treatment for primary duodenal GIST, including pancreaticoduodenectomy (PD) and local resection (LR). Researches reveal that the prognosis of duodenal GIST is determined by the pathologic factors of the tumor itself, and is not significantly associated with the surgical procedure. The intervention with targeted drugs such as imatinib has given the duodenal GIST more opportunities for LR. Meanwhile, the technique development of the laparoscopy combined with endoscopic surgery and robotic surgery ensures the steps of minimally invasive treatment for duodenal GIST into a new era.
