Indication selection and clinical application strategies of fecal microbiota transplantation
10.3760/cma.j.cn.441530-20200110-00015
- VernacularTitle:菌群移植适应证的选择和临床应用策略
- Author:
Xueying ZHANG
1
;
Qiyi CHEN
;
Ning LI
;
Huanlong QIN
Author Information
1. 同济大学附属第十人民医院肠道微生态诊疗中心 同济大学医学院肠道疾病研究所，上海 200072
- Keywords:
Fecal microbiota transplantation;
Indications;
Donor screening;
Quality control;
Clinical strategy
- From:
Chinese Journal of Gastrointestinal Surgery
2020;23(5):509-515
- CountryChina
- Language:Chinese
-
Abstract:
Fecal microbiota transplant (FMT) has become an effective method for the treatment of recurrent C. difficile infection. In addition, it has shown certain effects in other diseases inside and outside the intestine. A large number of clinical trials have been carried out. However, there is still lack of uniform standard for strategies of FMT. In this paper, we discussed the current hot and controversial issues of FMT from the aspects of indication, donor screening, fecal suspension quality control, methodology, follow-up and efficacy judgment, treatment of adverse reaction and ethical supervision based on our team's clinical experience.
