A Case of Late Onset Bleb-Related Endophthalmitis after Trabeculectomy with Mitomycin C.
- Author:
Young Gab KIL
1
;
Suck Man JIN
;
Dug Young CHUNG
Author Information
1. Department of Ophthalmology, Presbyterian Medical Center, Chonju, Korea.
- Publication Type:Case Report
- Keywords:
Endophthalmitis;
MMC;
Thin-walled blebs;
Trabeculectomy
- MeSH:
Anterior Chamber;
Anti-Bacterial Agents;
Blister;
Endophthalmitis*;
Glaucoma;
Hand;
Humans;
Mitomycin*;
Trabeculectomy*;
Visual Acuity;
Vitrectomy
- From:Journal of the Korean Ophthalmological Society
1999;40(7):2036-2042
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Adjunctive use of Mitomycin C (MMC)in trabeculectomy has greatly improved the success rate. Trabeculectomy with MMC, however, has resulted in a cystic and thin-walled filtering bleb, which may be more susceptible to infection. Late onset bleb-related endophthalmitis developed in a glaucoma patient at 40 months after MMC trabeculectomy. Filtering bleb in this patient had been avascular, thin-walled and cystic prior to the occurrence of endophthalmitis. Patient complained of decreased visual acuity with ocular discomfort and conjunctival injection and showed a mucopurulent infiltrate within the bleb, hypopyon and vitritis. Visual acuity was hand motion. An intensive treatment included anterior chamber irrigation, lensectomy,par plana vitrectomy, intravitreal and subconjunctival antibiotics (vancomycin,gentamycin) injection and topical and systemic corticosteroid (dexamethasone) and antibiotics,which led to a resolution.