Relationship between the relative variability of blood platelet count and the severity and prognosis of sepsis
10.12025/j.issn.1008-6358.2017.20160978
- VernacularTitle:血小板相对变化度与脓毒症患者病情严重程度及预后的关系
- Author:
Si-Meng PAN
1
;
Yu-Jing LIU
;
Hong-Yu HE
;
Yi-Jun ZHENG
;
Du-Ming ZHU
;
Zhe LUO
;
Min-Jie JU
Author Information
1. 复旦大学附属中山医院重症医学科
- Keywords:
sepsis;
blooplatelet count;
relativvariability;
mortality
- From:
Chinese Journal of Clinical Medicine
2017;24(2):286-289
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the relationship between the relative variability of the platelet count in peripheral blood and the severity and prognosis of sepsis patients.Methods:Clinical data of 102 sepsis patients admitted to the Department of Critical Care Medicine (ICU), Zhongshan Hospital, Fudan University from March 2015 to June 2016 were collected.The clinical characteristics of patients with high and low platelet relative variability were compared.The relationship between the relative variability of blood platelet count and the severity of disease and mortality were analyzed.Results:The relative variability of the platelet count was negatively associated with the SOFA (Spearman r=-0.317, P=0.001) and APACHE Ⅱ (Spearman r=-0.397, P<0.001) scores upon admission into ICU.Multivariate regression analysis showed that the relative variability of platelet count was an independent predictor of ICU mortality in sepsis patients (OR=0.174, 95% CI 0.040-0.758, P=0.02).Conclusions:The relative variability of platelet count in sepsis patients can reflect the severity of the disease and predict the ICU mortality of these patients.
