Evaluation of depression in obese patients with acanthosis nigricans

VernacularTitle:肥胖伴黑棘皮病患者抑郁状况调查分析
Author: Hui-Wei XU ¹ ; Yue-Ye HUANG ; She-Zhen YANG
Author Information

1. 江苏省海门市人民医院内分泌科
Keywords: obesity; depression; acanthosis nigricans
From: Chinese Journal of Clinical Medicine 2017;24(1):123-126
CountryChina
Language:Chinese
Abstract: Objective:To investigate the psychological depression of obese patients with acanthosis nigricans (AN), in order to provide evidence for clinical treatment.Methods:From March 2014 to August 2014,a total of 88 consecutive patients with obese were treated in our department,56 age-matched normal weight healthy volunteers were included as control group.They were divided into simple obesity group (OB,n= 30)and obesity with acanthosis nigricans group (AN,n= 58). The self-administrated Beck Depression Inventory-Ⅱ questionnaire was used in three groups,and general characteristics and clinical data were collected for analysis.Results:Compared with OB group,AN group had higher levels of FFA and UA (P<0.05).The severity of depression was significantly higher in AN group than OB group and the control group (P<0.05).The frequency of depression was recorded as 67.2% in the AN group,43.4% in OB group,and 3.6% in control group (P<0.05).Conclusions:Obese patients with AN has severer metabolism disorder and severity of depression than simple obesity patients.Psychotherapy is necessary for AN patients when treat for obesity .