The structure analysis of ectopic bone formed by engineered bone in the New-Zealand rabbits

VernacularTitle:新西兰大白兔组织工程骨的构建及体内异位成骨效果
Author: Hai-Xu LI ¹ ; Ji-Xiang SHI ; Wen-Jun SHI ; Fu-Ying LIU ; Shai-Lin ZHANG ; Qiang ZHOU
Author Information

1. 上海中医药大学附属普陀医院骨科
Keywords: engineered bone constructs; ectopic bone formation; structure
From: Chinese Journal of Clinical Medicine 2017;24(1):89-92
CountryChina
Language:Chinese
Abstract: Objective:To study the structure of ectopic bone formed beside the New-Zealand rabbit femoral bone. Methods:Bone marrow stroma stem cells (BMSCs)were taken from New-Zealand rabbits to built engineered bone constructs, the constructs were embedded near the rabbit femoral bone,the ectopic bone constructs were harvested at 8th week for further examination and study.Results:At 8th week,the ectopic bone had a clear bone-like structure,together with new blood supply, green fluorescent protein could be seen in samples seeded by marked cells.Conclusions:This study showed that the ectopic bone formation could be successfulinvivo.