Multiple factors in evaluating postoperative heart failure in elderly female patients with gynecological tumor
10.12025/j.issn.1008-6358.2016.20160304
- VernacularTitle:老年妇科肿瘤患者术后并发心衰的多因素分析
- Author:
Nan WANG
1
;
Ruo-Xi ZHANG
;
Jing-Bo HOU
;
Ling DONG
;
Sheng-Nan MENG
Author Information
1. 齐齐哈尔市中医医院妇产科
- Keywords:
gynecologic tumor;
elderly female;
postoperative;
heart failure
- From:
Chinese Journal of Clinical Medicine
2016;23(6):785-789
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive effects of multiple biomarkers on heart failure in elderly female patients with gynecologic tumor after surgery .Methods :This retrospective study included 416 elderly female patients with gynecologic tumor after surgical treatment .Patients were divided into the heart failure group and the non‐heart‐failure group according to the NYHA classification of cardiac insufficiency . All patients underwent physical examination , laboratory examination ,ECG ,heart color Doppler sonography and preoperative evaluation of gynecology before operation ,and the heart function was evaluated again by heart color Doppler sonography after operation . White blood cell count (WBC ) , electrocardiogram fragmented QRS complex (fQRS) ,serum cardiac troponin I (TnI) and N‐terminal pro brain natriuretic peptide (NT‐proBNP) were selected as evaluation indexes for predicting cardiac function .Results:The appearance of fQRS in heart failure group was significantly higher than that in non‐heart‐failure group ,and the difference was statistically significant (P< 0 .05) .The heart failure group had significantly higher WBC ,TnI ,and NT‐proBNP levels than the non‐heart‐failure group ,and the differences were statistically significant (P<0 .05) .The sensitivity of the combination of multiple biomarkers in predicting postoperative heart failure in elderly female with gynecological tumor was 96 .2% ,and the specificity was 85 .4% . Conclusions :The combination of multiple biomarkers can be used to predict postoperative heart failure in elderly female with gynecologic tumor with simple operation methods and effective prediction results .
