Analysis of recurrence factors of small intestine gastrointestinal stromal tumor after tumor resection based on single clinical center
10.12025/j.issn.1008-6358.2016.20150040
- VernacularTitle:小肠间质瘤术后复发影响因素分析：基于单中心数据的研究
- Author:
Jiang-Yong SANG
1
;
Xiao-Dong GAO
;
An-Wei XUE
;
Yong FANG
;
Ping SHU
;
Jia-Qian LING
;
Ying-Yong HOU
;
Kun-Tang SHEN
;
Jing QIN
;
Yi-Hong SUN
;
Xin-Yu QIN
Author Information
1. 新疆维吾尔自治区喀什地区第二人民医院普通外科
- Keywords:
gastrointestinal stromal tumor;
surgery;
prognosis
- From:
Chinese Journal of Clinical Medicine
2016;23(6):773-775
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the recurrence factors of small intestine gastrointestinal stromal tumor (GIST ) after resection .Methods :The clinicopathological data of 67 patients with recurrent small intestine GIST admitted to Zhongshan Hospital affiliated to Fudan University from January 2004 to December 2013 were retrospectively analyzed .Kaplan‐Meier method was used to analyze the effects of different factors on the recurrence time of small intestine GIST .Cox multi‐factor regression analysis was used to analyze the independent factors of recurrence of small intestine GIST .Results :Univariate analysis revealed that the median recurrence time significantly shortened in patients with tumor diameter more than 10 cm , mitotic rate greater than or equal to 30/50 HPF ,tumor rupture ,and R0 resection ,and the difference was significant (P<0 .05) .Multivariate analysis demonstrated that tumor rupture and surgical methods were independent prognostic factors for the recurrence of small intestine GIST (P< 0 .05) .Conclusions :R0 resection and intraoperative tumor rupture avoidance can prolong the recurrence time of small intestine GIST .
