Study on prognosis relationship between ABO blood groups of patients with gastric cancer
10.3760/cma.j.issn.1671-0274.2015.10.011
- VernacularTitle:ABO血型与胃癌患者预后关系的研究
- Author:
Shuao XIAO
1
;
Fan FENG
;
Li SUN
;
Guanghui XU
;
Xiao LIAN
;
Man GUO
;
Chao NAI
;
Zhen LIU
;
Shushang LIU
;
Lei ZHANG
;
Lei CAI
;
Jinqiang LIU
;
Hongwei ZHANG
Author Information
1. 第四军医大学附属西京医院消化一科
- Keywords:
Stomach neoplasms;
ABO blood group;
Clinicopathologic characteristics;
Prognosis
- From:
Chinese Journal of Gastrointestinal Surgery
2015;(10):1011-1015
- CountryChina
- Language:Chinese
-
Abstract:
[Abstact] Objective To investigate the relationship of ABO blood group with the clinicopathological characteristics in patients with gastric cancer and to assess whether the ABO blood group was associated with prognosis. Method Clinicopathological and follow-up data of 2838 patients with gastric cancer who underwent radical gastrectomy in our department from June 2008 to October 2013 were analyzed retrospectively. The distribution of ABO blood group under different clinicopathological characteristics and the overall 5-year survival of ABO blood group were compared. Results There were no significant differences in clinicopathological characteristics among patients with different ABO blood groups ﹙all P>0.05). The 5-year overall survival﹙OS) rates were 57.3% for patients with blood type A, 54.7% for type B, 57.4% for type O, and 53.5% for type AB. Though there was no significance difference of survival among ABO blood groups ﹙P=0.722), while the subgroup analysis indicated that stage Ⅲ patients of blood group Non-AB had a poorer OS compared to those of blood group AB ﹙25.2% vs. 44.7%, P=0.014); smoking patients of blood group Non-AB had a poorer OS compared to those of blood group AB ﹙53.4% vs. 74.9%, P=0.044). Conclusion Neither clinicopathological characteristics nor overall survival are associated with the ABO blood group, however, stage Ⅲ and smoking patients of blood group Non-AB have a poorer OS compared to those of blood group AB.
