Effect of body mass index on postoperative short-term outcomes of laparoscopy radical gastrectomy：a meta-analysis
10.3760/cma.j.issn.1671-0274.2015.08.028
- VernacularTitle:体质指数对腹腔镜胃癌根治术短期结局影响的Meta分析
- Author:
Lin HU
1
;
Changrong LI
;
Weifeng LI
;
Honglang LI
Author Information
1. 330006,南昌大学第二附属医院胃肠外科
- Keywords:
Body mass index;
Laparoscopy;
Stomach neoplasms;
Gastrectomy;
Meta-analysis
- From:
Chinese Journal of Gastrointestinal Surgery
2015;(8):826-831
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of body mass index (BMI) on postoperative short-term outcomes of laparoscopy radical gastrectomy by meta-analysis. Methods A literature search was performed in PubMed, EMBASE, Cochrane Library databases, CNKI, and CBM, Wanfang database to screen clinical trials published before October 2014 that compared short-term outcomes between high BMI and low BMI patients undergoing laparoscopy radical gastrectomy. RevMan 5.2 was used to perform the meta-analysis. Begg′s and Egger′s tests were carried out with Stata 12.0 software to evaluate the publication bias of enrolled literatures. Results Twelve studies involved a total of 4798 gastric cancer patients after laparoscopy radical gastrectomy. There were 1215 patients in high BMI group (BMI≥25 kg/m2) and 3583 patients in the low BMI group (BMI <25 kg/m2). Compared with the low BMI group, the high BMI group were associated with longer operation time (SMD=0.64, 95%CI:0.35-0.93, P=0.000), more intraoperative blood loss (SMD=0.63, 95%CI:0.24-1.03, P=0.002), less retrieved lymph nodes (SMD=-0.44, 95%CI:-0.72--0.17, P=0.002), and more postoperative complications (OR=1.44, 95%CI:1.19-1.74, P=0.000). There were no significant differences in postoperative hospital stay, the time to first flatus and initial complication (P>0.05). Conclusion The higher BMI may result in a longer operation time, more intraoperative blood loss and a higher rate of postoperative complication after laparoscopy radical gastrectomy.
