Comparison of effects of hand-assisted laparoscopic and traditional laparoscopic right hemicolectomy on immune function
10.3760/cma.j.issn.1671-0274.2015.08.026
- VernacularTitle:手辅助腹腔镜与传统腹腔镜右半结肠切除术对机体免疫功能影响的对比研究
- Author:
Tie LIU
1
;
Peng GUO
;
Xiaogang LENG
Author Information
1. 261041,山东省潍坊市人民医院肛肠外科
- Keywords:
Colonic neoplasms;
Laparoscopy hand-assisted surgery;
Immune function
- From:
Chinese Journal of Gastrointestinal Surgery
2015;(8):817-820
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of hand-assisted laparoscopic and traditional laparoscopic right hemicolectomy on immune function. Methods From May 2010 to November 2013, 60 patients with right colon carcinoma were prospectively enrolled and randomly divided into hand-assisted laparoscopic surgery(HALS) group and traditional laparoscopic surgery(TLS) group with 30 cases in each group. CRP, IL-6, CD3+, CD4+, CD8+ in the peripheral blood were measured and compared on the first day before operation, the first, third and fifth day after operation. Results CRP and IL-6 levels in two groups were significantly increased on the first, third and fifth days (P<0.01), and peaked on the third day after operation. Postoperative CRP and IL-6 levels were slightly higher in HALS group, but the difference was not statistically significant (P>0.05). CD3+and CD4+levels were significantly decreased on the first, third day after operation (P<0.05), and returned to preoperative levels on the fifth day after operation in both two groups , and the difference was not statistically significant (P>0.05). There was no significant difference in CD8+ between two groups either before surgery or after operation (P>0.05). Conclusion Hand-assisted laparoscopic right hemicolectomy has the same effects of traditional laparoscopic right hemicolectomy in the relief of postoperative stress and the protection of immune function.
