Application of sevoflurane combined with propofol anesthesia maintenance in general anesthesia combined with epidural anesthesia
- VernacularTitle:七氟醚联合丙泊酚麻醉维持在全麻复合硬膜外麻醉中的临床应用
- Author:
Chao LIANG
1
;
Ming DING
;
Fang DU
;
Jing CANG
;
Zhang-Gang XUE
Author Information
1. 复旦大学附属中山医院麻醉科
- Keywords:
propofol;
sevoflurane;
general anesthesia
- From:
Chinese Journal of Clinical Medicine
2016;23(3):324-326
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare the effects of propofol combined with sevoflurane on maintenance of general anesthesia with sevoflurane alone for maintenance of anesthesia for patients’ recovery .Methods:160 patients scheduled for gastrointestinal surgery under epidural block combined with general anesthesia were randomly divided into sevoflurane group (group S ,n= 80) and sevoflurane/propofol group (group SP ,n= 80) .After induction ,anesthesia was maintained with sevoflurane in group S and sevoflurane combined with propofol (1 .2 μg/mL) in group SP .Bispectral Index (BIS) values were maintained at 40-60 during the maintenance of anesthesia .The time to extubation ,the incidence of serious cough and agitation during emergence ,and other related events were recorded .Results:The recovery time and the time to extubation in the SP group were (7 .2 ± 2 .0) min and (8 .0 ± 1 .8) min ,respectively ,the recovery time and the time to extubation of the S group were (12 .3 ± 1 .5) min and (12 .8 ± 1 .6) min ,and the difference was statistically significant (P< 0 .05) .The incidence of serious coughing and agitation in SP group (30% and 25% ) were significantly lower than that of group S (68% and 53% ,P<0 .05) .There was no significant difference in BIS value ,the dosage of fentanyl and muscle relaxants during anesthesia between the two groups .Conclusions:Compared with sevoflurane maintenance , sevoflurane combined with propofol for anesthesia maintenance shortens the recovery time and leads to lower incidence of emergence coughing and agitation .
