Long-term prognosis of cobalt-chromium sirolimus-eluting stent implantation in patients with coronary heart disease complicated with diabetes mellitus
- VernacularTitle:国人冠心病合并糖尿病患者接受雷帕霉素洗脱钴铬合金支架植入术后的长期预后分析
- Author:
Yue-Yi PAN
1
;
Wahafu MAMUTI
;
Wu-Xu ZUO
;
Ji-E YANG
;
Feng ZHANG
;
Ju-Ying QIAN
;
Lei GE
;
Jun ZHOU
;
Jun-Bo GE
Author Information
1. 复旦大学附属中山医院心内科
- Keywords:
coronary artery disease;
diabetes mellitus;
drug-eluting stent;
cobalt-chromium
- From:
Chinese Journal of Clinical Medicine
2016;23(3):286-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the long-term efficacy and safety of a novel type of cobalt-chromium sirolimus-eluting stent (CoCr-SES) in patients with coronary artery disease (CAD) complicated with diabetes mellitus (DM ) .Methods:A total of 1 045 Chinese patients with DM were enrolled into a prospective ,multicenter registered research and followed up for the incidence of death ,myocardial infarction (MI) ,blood circulation reconstruction and thrombosis (ST) among other events . The primary endpoint was a major adverse cardiovascular event (MACE) ,which was composed of cardiovascular death ,non-fatal myocardial infarction (MI) and target vessel revascularization (TVR) ,with a clinical follow-up of 3 years .Results:During the 3-year follow-up ,among 1 045 cases of coronary heart disease complicated with diabetes mellitus ,the rate of MACE was 10 .0% ,including 41 cases (3 .9% ) of cardiovascular death ,38 cases (3 .6% ) of non-fatal MI and 25 cases (2 .4% ) of TVR . The incidence of stent thrombosis (ST ) was 1 .1% in 3 years ,including 7 cases (0 .7% ) of early ST and 4 cases (0 .4% ) of advanced ST .Conclusions:The incidence of MACE and ST is low in patients with coronary heart disease complicated with diabetes at 3 years after implantation of CoCr-SES ,providing compelling evidence for the wide use of domestic CoCr-SES in patients with coronary heart disease complicated with diabetes .
